Analysis of Two Polymorphic Forms of a Pyrido[2,3-d]pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex with Human Dihydrofolate Reductase
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Analysis of Two Polymorphic Forms of a Pyrido[2,3-d]pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex with Human Dihydrofolate Reductase Descriptor: 2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate Reductase, SULFATE ION Authors: Cody, V, Galitsky, N, Luft, J.R, Pangborn, W.A, Gangjee, A. Deposit date: 2002-09-26 Release date: 2003-04-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
人二氢叶酸还原酶(human dihydrofolate reductase)结合的吡啶并[2,3-d]嘧啶N9-C10反向桥接抗叶酸剂二元复合物的两种多晶型分析 描述物:2,4-二氨基-6-[N-(3',4',5'-三甲氧基苄基)-N-甲氨基]吡啶并[2,3-d]嘧啶、二氢叶酸还原酶(Dihydrofolate Reductase)、硫酸根离子 作者:Cody, V、Galitsky, N、Luft, J.R、Pangborn, W.A、Gangjee, A 存入日期:2002-09-26 发布日期:2003-04-01 最后修改日期:2024-02-14 研究方法:X射线衍射(X-RAY DIFFRACTION,分辨率1.8 Å) 引用文献:人二氢叶酸还原酶结合的吡啶并[2,3-d]嘧啶N9-C10反向桥接抗叶酸剂二元复合物的两种多晶型分析。《晶体学报D辑》(Acta Crystallogr.,Sect.D),59卷,2003年



