P. aeruginosa LpxA in complex with ligand L13
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P. aeruginosa LpxA in complex with ligand L13 Descriptor: (3S)-3-(5,5-dimethyl-2-oxo-1,3-oxazolidin-3-yl)-N-(1H-tetrazol-5-yl)-1-[3-(trifluoromethyl)benzoyl]-2,3-dihydro-1H-indole-3-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, ... Authors: Sacco, M, Chen, Y. Deposit date: 2021-12-13 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-Based Ligand Design Targeting Pseudomonas aeruginosa LpxA in Lipid A Biosynthesis. Acs Infect Dis., 8, 2022
铜绿假单胞菌（Pseudomonas aeruginosa，缩写P. aeruginosa）LpxA与配体L13的复合物 描述符：(3S)-3-(5,5-二甲基-2-氧代-1,3-噁唑烷-3-基)-N-(1H-四唑-5-基)-1-[3-(三氟甲基)苯甲酰基]-2,3-二氢-1H-吲哚-3-甲酰胺、2-氨基-2-羟甲基-1,3-丙二醇、酰基-[酰基载体蛋白（acyl-carrier-protein）]-UDP-N-乙酰葡糖胺O-酰基转移酶…… 作者：Sacco, M、Chen, Y。存入日期：2021-12-13 发布日期：2022-07-06 最后修改日期：2023-10-18 实验方法：X射线衍射 (2 Å) 引用文献：《靶向铜绿假单胞菌脂A生物合成通路中LpxA的基于结构的配体设计》，《ACS Infectious Diseases》，第8卷，2022年
