phiC31 integrase’s binding sequences in bos taurus. Bos taurus

NIAID Data Ecosystem2026-03-09 收录

位点特异性基因整合

牛基因组编辑

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA347615 数据链接链接失效反馈

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资源简介：

To study the role of DNA sequence recognition in guiding phiC31-mediated site-specific integration in bovine genome.

创建时间：

2016-10-11

Lipofection of Purified Adeno-Associated Virus Rep68 Protein: toward a Chromosome-Targeting Nonviral Particle

基因递送系统

位点特异性基因整合

Adeno-associated virus (AAV) integrates very efficiently into a specific site (AAVS1) of human chromosome 19. Two elements of the AAV genome are sufficient: the inverted terminal repeats (ITRs) and th

PubMed Central60

An efficient method to successively introduce transgenes into a given genomic locus in the mouse

转基因小鼠模型构建

位点特异性基因整合

BACKGROUND: Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability of well-characterized promoters

PubMed Central2001-06-19 更新10

Cas9-expressing cattle using the transposon all-in-one Cas9 for bovine genome editing

转基因牛模型构建

牛基因组编辑

These data demonstrate, for the first time, that Cas9-expressing cattle were successfully born, and this transgene was transmitted to the next-generation calves (F1) and F2 embryos. In addition, somat

NIAID Data Ecosystem00

Site-Specific Integration in Mammalian Cells Mediated by a New Hybrid Baculovirus–Adeno-Associated Virus Vector

基因治疗载体

位点特异性基因整合

Baculovirus can transiently transduce primary human and rat hepatocytes, as well as a subset of stable cell lines. To prolong transgene expression, we have developed new hybrid vectors which associate

PubMed Central20

Single-copy transgenic mice with chosen-site integration.

转基因小鼠模型

位点特异性基因整合

We describe a general way of introducing transgenes into the mouse germ line for comparing different sequences without the complications of variation in copy number and insertion site. The method uses

PubMed Central1996-08-20 更新00

phiC31 integrase’s binding sequences in bos taurus. Bos taurus

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