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High complexity cellular barcoding and clonal tracing reveals stochastic and deterministic parameters of radiation resistance

ChEBI2021-09-07 更新2026-07-12 收录

辐射抗性机制

克隆演化追踪

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-9693 数据链接链接失效反馈

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High complexity cellular barcoding and clonal tracing reveals stochastic and deterministic parameters of radiation resistance

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2021-09-07

急性髓系白血病

克隆演化追踪

Mutations in the nucleophosmin 1 (NPM1) gene are considered founder mutations in the pathogenesis of acute myeloid leukemia (AML). To further characterize the genetic composition of NPM1 mutated (NPM1

NIAID Data Ecosystem60

Escherichia coli MG1655 IR-11-88 population Resequencing. Escherichia coli strain:MG1655 IR-11-88

微生物基因组学

辐射抗性机制

Resequencing to identify the molecular basis of resistance to ionizing radiation in evolved populations of Escherichia coli

NIAID Data Ecosystem40

Expression and Mutational Analysis of DinB-Like Protein DR0053 in Deinococcus radiodurans

辐射抗性机制

DNA损伤修复

In order to understand the mechanism governing radiation resistance in Deinococcus radiodurans, current efforts are aimed at identifying potential candidates from a large repertoire of unique Deinococ

NIAID Data Ecosystem40

DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy [DNA barcodes: WT_nude_and_NSG_4T1_BC5000]. DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy [DNA barcodes: WT_nude_and_NSG_4T1_BC5000]

肿瘤免疫编辑

克隆演化追踪

To investigate immunoediting at the primary tumour, we used DNA barcoding combined with NGS. By stably integrating 4T1 murine cancer cell line with 5000 unique DNA barcodes (1 barcode per cell), we ca

NIAID Data Ecosystem50

Data_Sheet_1_The Transcription Factor Hif-1 Enhances the Radio-Resistance of Mouse MSCs.pdf

辐射抗性机制

骨髓微环境

Mesenchymal stromal cells (MSCs) are multipotent progenitors supporting bone marrow hematopoiesis. MSCs have an efficient DNA damage response (DDR) and are consequently relatively radio-resistant cell

NIAID Data Ecosystem40

High complexity cellular barcoding and clonal tracing reveals stochastic and deterministic parameters of radiation resistance

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