Crystal Structure of small molecule ARS-853 covalently bound to K-Ras G12C
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Crystal Structure of small molecule ARS-853 covalently bound to K-Ras G12C Descriptor: 1-[3-[4-[2-[[4-chloranyl-5-(1-methylcyclopropyl)-2-oxidanyl-phenyl]amino]ethanoyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one, GLYCEROL, GLYCINE, ... Authors: Patricelli, M.P, Janes, M.R, Li, L.-S, Hansen, R, Peters, U, Kessler, L.V, Chen, Y, Kucharski, J.M, Feng, J, Ely, T, Chen, J.H, Firdaus, S.J, Babbar, A, Ren, P, Liu, Y. Deposit date: 2015-12-01 Release date: 2016-01-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State. Cancer Discov, 6, 2016
创建时间：
2015-12-01
