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Enriched Single-Nucleus RNA-Sequencing Reveals Unique Attributes of Distal Convoluted Tubule Cells

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE228367
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Distal convoluted tubule (DCT) cells display a remarkable ability to adapt to the dietary potassium intake. We applied single-nucleus RNA-seq to map the plasticity of enriched mouse DCT cells in response to dietary potassium restriction Kidney DCT cells of the NCC-Cre-INTACT mice were isolated by Fluorescence-activated nuclei sorting (FANS) according to the presence or absence of mCherry signal and analyzed using scRNAseq.
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2024-04-02
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