Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355

Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355 Descriptor: (1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, L, Jin, Y, Davies, G.J. Deposit date: 2016-06-13 Release date: 2017-05-31 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017人类肝素酶原（proheparanase）与葡萄糖醛酸构型氮丙啶探针JJB355结合的晶体结构。描述符：(1S,2R,3S,4S,5S,6R)-2-(8-叠氮辛基氨基)-3,4,5,6-四羟基环己烷-1-羧酸、1,2-乙二醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖等。作者：Wu, L、Jin, Y、Davies, G.J.。提交日期：2016-06-13，发布日期：2017-05-31，最后修改日期：2024-11-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.94 Å。引用文献：《用于活性保留型β-葡萄糖醛酸苷酶功能解析的活性探针》，《自然·化学生物学（Nat. Chem. Biol.）》，第13卷，2017年。