Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Deoxy-5'-Methylioadenosine and 4-Aminomethylaniline

Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Deoxy-5'-Methylioadenosine and 4-Aminomethylaniline Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(aminomethyl)aniline, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... Authors: Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Person, L. Deposit date: 2014-06-03 Release date: 2014-10-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015恶性疟原虫（Plasmodium Falciparum）精脒合酶（Spermidine Synthase）与5'-脱氧-5'-甲硫腺苷（5'-Deoxy-5'-Methylthioadenosine）及4-氨基甲基苯胺（4-Aminomethylaniline）复合物的晶体结构 组分：2-(2-{2-[2-(2-甲氧基乙氧基)乙氧基]乙氧基}乙氧基)乙醇、4-(氨基甲基)苯胺、5'-脱氧-5'-甲硫腺苷…… 作者：Sprenger J、Halander J.C、Svensson B、Al-Karadaghi S、Person L 提交日期：2014-06-03 发布日期：2014-10-08 最后修改日期：2024-01-10 检测方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.05埃（Å） 引用文献：《结合抑制剂的恶性疟原虫精脒合酶三维结构为药物设计提供新策略》，刊载于《晶体学报D辑》（Acta Crystallographica Section D），2015年，第71卷。