Effects of dietary methionine supplementation on vaccination efficacy in rainbow trout

Methionine, an essential amino acid, participates in various pathways with implications for the immune system. Recent evidence suggests that it may support both innate and adaptive immune mechanisms. In the present study, it was hypothesized that dietary methionine supplementation prior to vaccination may be a promising strategy to improve vaccine efficacy. Hence, the current research aimed to evaluate the effects of dietary methionine supplementation on the immune status of rainbow trout (Oncorhynchus mykiss) juveniles, its role in modulating immune responses, as well as its potential synergistic effects with a commercial vaccine.