Molecular characterization of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
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https://www.omicsdi.org/dataset/ega/EGAS00001005222
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资源简介：
Patients with hepatocellular carcinoma (HCC) associated to non-alcoholic steatohepatitis (NASH) are increasing globally, but their molecular traits are not well characterized. Our molecular characterization revealed higher rates of ACVR2A mutations (10%) – a potential tumour suppressor, presence of a novel mutational signature (MutSig-NASH-HCC), a more relevant role of Wnt/TGF-β proliferation subclass in tumours (42%) and immunosuppressive traits in the adjacent non-tumoral tissue.EGA study EGAS00001005222
创建时间：
2021-04-27
