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Transcription profiling of Rattus norvegicus liver cells: sham vs rats after bile duct ligation procedure
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创建时间：
2015-10-22
相关数据集
Expression data of the livers of male C57Bl6/N mice after bile duct ligation. Expression data of the livers of male C57Bl6/N mice after bile duct ligation
Bile duct ligation is a commonly used technique to induce obstructive cholestasis in mice. Overall design: 8 to 10 week-old C57BL/6N mice (male) were used. The extrahepatic common bile duct was ligate
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The Farnesoid X receptor (FXR), is the main bile acids sensor expressed in hepatocytes. Obeticholic acid (OCA), a fairly potent FXR agonist, has been approved for the treatment of UDCA-resistant PBC,
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Circulating bile acids and TNF-α levels in CBDL and PVL animals.
Values are expressed as means ± SME; n = 5–8 animals per group. CBDL, common bile duct ligation; PVL, partial portal vein ligation. * P<0.05 compared with control. Circulating bile acids and TNF-α lev
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Analysis of gut microbiota in mice with bile duct obstruction after biliary drainage
The abundance of specific gut microorganism is strongly associated with the concentrations of microbially modified bile acids. This research aimed at investigating the composition of intestinal microb
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