Whole genome sequencing of the HCT116 and HKE3 cell lines. Homo sapiens

NIAID Data Ecosystem2026-03-10 收录

结直肠癌基因组学

EGF信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA374513 数据链接链接失效反馈

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资源简介：

Whole genome sequencing of the HCT116 and HKE3 colorectal cancer cell lines related to a study of the EGFR network in cancer.

创建时间：

2017-02-13

Supplementary Material for: Egr-1 Maintains NSC Proliferation and Its Overexpression Counteracts Cell Cycle Exit Triggered by the Withdrawal of Epidermal Growth Factor

神经干细胞

EGF信号通路

In adult mammals, neural stem cells (NSCs) reside in specialized niches at the level of selected CNS regions, such as the subventricular zone (SVZ). The signaling pathways that regulate NSC prolifera

DataCite Commons2020-08-28 更新120

Supplementary Table 3 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

结直肠癌基因组学

癌症突变检测

XLSX file - 45KB, Sanger sequencing validation for mutations detected by exome-capture sequencing for 12 genes in 43 CRC cell lines. Genes comprised APC, CTNNB1, KRAS, BRAF, NRAS, PIK3CA, PTEN, SMAD2,

NIAID Data Ecosystem20

Intronic SNPs near splice sites (<30 nt).

基因组SNP分析

结直肠癌基因组学

aTissue samples with SNP detected by NGS. CRC is the colorectal cancer tissue, and CRN is the colorectal cancer adjacent normal tissue. b“+” indicates “validated” and “−” indicated “not tested” by Seq

NIAID Data Ecosystem20

TAD Variance Promotes Cancer Driver Genes through Redistribution of Super-Enhancers. HCT116 and NCM460 cell lines

结直肠癌基因组学

染色体三维结构

chromosome 3D structure in colorectal cancer

NIAID Data Ecosystem70

Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human colorectal cancer risk [ATAC-seq]. Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human colorectal cancer risk [ATAC-seq]

结直肠癌基因组学

增强子-基因调控

Although GWASs have identified thousands of variants associated with human complex traits, most of which reside in the non-coding regions, especially enhancers, and biological mechanisms remain unclea

NIAID Data Ecosystem20

Whole genome sequencing of the HCT116 and HKE3 cell lines. Homo sapiens

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