Bacteroides uniformis and Anaerostipes hadrus Combined with Galactooligosaccharide Ameliorate C. difficile Infection and Neuroinflammation via the Gut-Brain Axis

The synergistic approach effects of B. uniformis, A. hadrus, and GOS demonstrateds the significant therapeutic potential for their use in CDI by restoring intestinal barrier integrity, modulating microbial diversity, and mitigating memory deficit mediated through the gut-brain axis intervention. These findings provide novel insights into potential therapeutic strategies for the managing management of CDI and associated neurological complications.