C. elegans stress-induced gene expression in low SAM or after histone-methytransferase RNAi

NIAID Data Ecosystem2026-03-10 收录

线虫应激基因表达

组蛋白甲基化调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE121511 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2018-10-22

ChIP-seq of histone methylation marks in YB5 cells

ChIP-seq表观遗传学

组蛋白甲基化调控

ChIP-seq of H3K4me2, H3K9me2, and H3K27me3 was performed in YB5 cells to determine the impact of baseline histone methylation patterns on gene reactivation by epigenetic therapy Biological duplicates

NIAID Data Ecosystem90

Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis

纤维化治疗

组蛋白甲基化调控

Activity of H3K9 histone methyltransferase G9a is reportedly induced by transforming growth factor-β1 (TGF-β1) and plays an important role in the progression of cancer and fibrosis. In this study, we

NIAID Data Ecosystem40

HEK293T cells treated with a G9a small molecule inhibitor (UNC0638) or vehicle (DMSO), WIZ siRNA, G9a siRNA, or scrambled (control) siRNA

表观遗传学

组蛋白甲基化调控

Transcriptional profiling of HEK293T cells following treatment with a small molecule inhibitor of catalytic activity of the G9a lysine methyltransferase (UNC0638, 1 micromolar, 48 hours), or siRNA aga

NIAID Data Ecosystem20

Dot1-Dependent Histone H3K79 Methylation Promotes the Formation of Meiotic Double-Strand Breaks in the Absence of Histone H3K4 Methylation in Budding Yeast

减数分裂重组

组蛋白甲基化调控

Epigenetic marks such as histone modifications play roles in various chromosome dynamics in mitosis and meiosis. Methylation of histones H3 at positions K4 and K79 is involved in the initiation of rec

Figshare2016-01-18 更新50

Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

组蛋白甲基化调控

表观遗传稳定性

Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and the regulation of gene expression. The establishment and epigenetic maintenan

NIAID Data Ecosystem30

C. elegans stress-induced gene expression in low SAM or after histone-methytransferase RNAi

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