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Gold-Catalyzed Intramolecular Indole/Alkyne Cyclization Cascades through a Heterolytic Fragmentation: 1,5-Indole Migration and Allenylation

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https://figshare.com/articles/dataset/Gold_Catalyzed_Intramolecular_Indole_Alkyne_Cyclization_Cascades_through_a_Heterolytic_Fragmentation_1_5_Indole_Migration_and_Allenylation/2767870
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Gold-catalyzed intramolecular reactions of 3-alkynyl-bearing indoles with diol groups lead to the formation of highly functionalized 3-allenylindoles with high efficiency. The reaction likely proceeds by a new gold-catalyzed cascade cyclization/heterolytic fragmentation/elimination reactions, which results in 1,5-indole migration and C-3 allenylation of indole moiety.
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2010-05-21
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