Artificial Macrocycles by Ugi Reaction and Passerini Ring Closure
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https://figshare.com/articles/dataset/Artificial_Macrocycles_by_Ugi_Reaction_and_Passerini_Ring_Closure/3830859
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资源简介：
Artificial macrocycles can be convergently synthesized by a sequence of an Ugi multicomponent reaction (MCR) followed by an intramolecular Passerini MCR used to close the macrocycle. Significantly, in this work, the first intramolecular macrocyclization through a Passerini reaction is described. We describe 21 macrocycles of a size of 15–20. The resulting macrocyclic depsipeptides are model compounds for natural products and could find applications in drug discovery.
创建时间：
2016-10-03
