RNAseq of 2'3' cGAMP injected Drosophila melanogaster
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE140955
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资源简介：
We recently reported that an orthologue of STING regulates infection by picorna-like viruses in drosophila. Here, we show that injection of flies with 2’3’-cGAMP can induce expression of dSTING-regulated genes. Analysis of the transcriptome of 2’3’-cGAMP injected flies reveals a complex pattern of response, with early and late induced genes. Our results reveal that dSTING regulates an NF-κB -dependent antiviral program, which predates the emergence of Interferon Regulatory Factors and interferons in vertebrates. RNAseq of Tris, ci-di-GMP and 2'3' cGAMP injected Drosophila melanogaster
创建时间：
2020-08-31
