Comparison of descriptive disease presentation and molecular findings in mice infected with monkeypox virus (MPXV).

C57BL/6 and BALB/c mice were challenged with either Congo Basin MPXV or West African MPXV by an intranasal (IN) or foot pad (FP) route of infection (n = 5 in each group). Samples for PCR and serology were taken at 30 days post infection.¶Mild swelling noted.†Severe swelling noted.*Severe limping with some animals putting little/no weight on limb.‡More than 1 sample positive or inconclusive.Inc: Inconclusive PCR sample.Positive/Inconclusive PCR samples: Li (liver), LN (lymph node), Sk (skin), RS (rectal swab), Lu (lung), BL (blood), Ki (kidney), Sp (spleen).