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Identification of an intermediate activation state of PAK5 reveals a novel mechanism of kinase inhibition.

NIAID Data Ecosystem2026-05-02 收录

酶抑制机制

PAK5激活状态

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https://www.rcsb.org/structure/8C12 数据链接链接失效反馈

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Identification of an intermediate activation state of PAK5 reveals a novel mechanism of kinase inhibition.

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创建时间：

2024-10-16

蛋白质结构解析

酶抑制机制

C-terminal domain of KipI from Bacillus subtilis Descriptor: Kinase A inhibitor Authors: Langley, D.B, Jacques, D.A. Deposit date: 2008-06-24 Release date: 2009-01-20 Last modified: 2023-11-01 Method:

Protein Data Bank Japan2023-11-01 更新60

Di-, Tri-, and Tetranuclear Zinc Hydroxamate Complexes as Structural Models for the Inhibition of Zinc Hydrolases by Hydroxamic Acids

杂金属配合物

酶抑制机制

Attempts to produce Zn analogues of the structural model complexes [M2(μ-O2CR)2(O2CR)2(μ-H2O)(tmen)2] (M = Ni, Co, Mn; R = CH3, C(CH3)3, CF3) by the reaction of a series of zinc carboxylates with N,N,

NIAID Data Ecosystem50

Sodium pumping NADH-quinone oxidoreductase with inhibitor DQA

酶抑制机制

呼吸链酶学

Sodium pumping NADH-quinone oxidoreductase with inhibitor DQA

NIAID Data Ecosystem00

Structure of a highdose liganded bacterial catalase

蛋白质结构解析

酶抑制机制

Structure of a highdose liganded bacterial catalase Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CATALASE, CHLORIDE ION, ... Authors: Gumiero, A, Walsh, M. Deposit dat

Protein Data Bank Japan2024-05-08 更新60

Structure of K57A hPNMT with inhibitor 7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy

蛋白质晶体学

酶抑制机制

Structure of K57A hPNMT with inhibitor 7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy Descriptor: N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, Phenylethanolamine N-methyltransfe

Protein Data Bank Japan2024-10-09 更新10

Identification of an intermediate activation state of PAK5 reveals a novel mechanism of kinase inhibition.

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