Crystal structure of human PI3K-gamma in complex with Compound 4
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Crystal structure of human PI3K-gamma in complex with Compound 4 Descriptor: 5-[2-amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Walker, N.P, Jeffrey, J.L. Deposit date: 2020-07-13 Release date: 2020-09-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Discovery of Potent and Selective PI3K gamma Inhibitors. J.Med.Chem., 63, 2020
创建时间：
2020-07-13
