11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one Descriptor: (4S)-4-(2-methoxyphenyl)-3,3-dimethyl-1-[3-(methylsulfonyl)phenyl]azetidin-2-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: McCoull, W, Augustin, M, Blake, C, Ertan, A, Kilgour, E.K, Krapp, S, Moore, J.E, Newcombe, N.J, Packer, M.J, Rees, A, Revill, J, Scott, J.S, Selmi, N, Gerhardt, S, Ogg, D.J, Steinbacher, S, Whittamore, P.R.O. Deposit date: 2013-11-15 Release date: 2014-03-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification and optimisation of 3,3-dimethyl-azetidin-2-ones as potent and selective inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1) TO BE PUBLISHED
创建时间：
2013-11-15
