Expression data from the carotid artery at 2 wks after Intimal injury

Injury of the arterial endothelial lamina, also called intimal injury, usually occurs after carotid endarterectomy, peripheral artery brachytherapy, stent placement for arterial occlusive disease and balloon dilatation surgeries. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Overall design: The intimal injury arteries harvested after 2 wks, and the undamaged right carotid artery served as the self-control, then performed transcriptome sequencing.