Clinical Characteristics of Go-DARTS Study Participants Stratified by PNPLA3 I148M Genotype.

Abbreviations: Go-DARTS, Genetics of Diabetes Audit and Research Tayside Scotland; PNPLA3, patatin-like phospholipase domain-containing 3; II, individuals with two 148I alleles; MM, individuals with two 148M alleles; IM, heterozygotes; n, number; HOMA-IR, homeostasis model assessment for insulin resistance HDL, high-density lipoprotein; ALT, alanine transferase; HbA1c, glycated hemoglobin; ns, P value≥0.05.
Plus-minus values are means ± SD.
*P values were calculated using linear regression model including age, body-mass index and gender for all variables. HOMA-IR, triglycerides and ALT were log-transformed before entering the model. See methods for more details on the statistical analyses.