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LARP1 mRNP scaffolds mTORC1 to stimulate translation initiation of an essential class of mRNAs

ChEBI2014-07-31 更新2026-07-21 收录

mRNA翻译调控

mTOR信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-59599 数据链接链接失效反馈

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LARP1 mRNP scaffolds mTORC1 to stimulate translation initiation of an essential class of mRNAs

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创建时间：

2014-07-31

果蝇生物学

mRNA翻译调控

The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first tw

NIAID Data Ecosystem90

Metastasis and Survival of Breast Cancer Stem Cells Mediated by Cytoskeleton Remodeling and PI3K/mTOR Signaling transcription factors

癌细胞转移机制

mTOR信号通路

Cancer metastasis is a fetal problem that claims life of over 90% of cancer patients. It is hypothesized that cancer stem cells (CSCs) mediate cancer metastasis and such cells are often resistant to c

NIAID Data Ecosystem50

mRNA seq of total and polysome associated mRNAs in three different conditions. mRNA seq of total and polysome associated mRNAs in three different conditions

mRNA翻译调控

RNA测序

We report on how the presence or absence of a 18 nt long ribosome-bound RNA affects the translation in S. cerevisiae. We observe that translation of all mRNAs is downregulated when the RNA is present.

NIAID Data Ecosystem40

MOESM2 of Excitotoxic glutamate causes neuronal insulin resistance by inhibiting insulin receptor/Akt/mTOR pathway

mTOR信号通路

钙信号

Additional file 2: Table S3. Raw data of [Ca2+]i (Fura-FF f340/f380 fluorescence) measurements.

DataCite Commons2020-08-26 更新70

Estrogen sensing by GPER1 activates PI3K/mTOR to promote gender dimorphism in liver growth and cancer. Danio rerio

肝癌性别差异

mTOR信号通路

Liver cancer is a common cause of cancer death, with a male-predominant incidence due, in part, to increased estrogen levels in cirrhotic patients. It is unknown, however, how estrogen is sensed to in

NIAID Data Ecosystem50

LARP1 mRNP scaffolds mTORC1 to stimulate translation initiation of an essential class of mRNAs

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