Comprehensive analysis of the complexity and heterogeneity of the lncRNAs transcriptome in multiple myeloma

RNA-seq analysis comparing the transcriptional landscape of LINC-SMILO silenced cells versus control cells in KMS-11 multiple myeloma cell line. Overall design: KMS-11 multiple myeloma cell line was transduced in duplicate with pLKO.1-puro vector containing a scramble or a shRNA expressing lentiviral system targeting LINC-SMILO gene. Samples were harvested after 4 days of shRNA infection.