Structure-guided design of partial agonists at an opioid receptor

Figshare2025-03-14 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Structure-guided_design_of_partial_agonists_at_an_opioid_receptor/26240981 数据链接链接失效反馈

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These files includes the maps and PDBs related to the data presented in the manuscript.

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2025-03-14

Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design

激酶抑制剂开发

结构引导药物设计

Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design Descriptor: 1-benzyl-N-(5-{5-[3-(dimethylamino)-2,2-dimethylpropoxy]-1H-indol-2-yl}-6-oxo-1,6-dihydropyri

Protein Data Bank Japan2024-01-10 更新60

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement

癌症表观遗传药物

结构引导药物设计

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Histone-lysine N-methyltransferase, ... Authors: Xu, X, Dhe-Paganon, S, Blacklow, S. D

Protein Data Bank Japan2023-09-27 更新50

Structure–Activity Studies of a Novel Opioid Cyclic Hexapeptide Modified at Gly3: Identification of Highly Potent Agonists or Antagonists of Opioid Receptors

阿片受体药物发现

肽类结构活性关系

Subtle structural modifications at the 3-position of opioid peptides have been reported to modulate their receptor binding affinity and functional activity. Our previous work identified a novel cyclic

Figshare2026-03-06 更新30

HumRadA1.2 soaked with napht-2,3-diol overnight at 1 mM

蛋白质晶体学

结构引导药物设计

HumRadA1.2 soaked with napht-2,3-diol overnight at 1 mM Descriptor: PHOSPHATE ION, RadA, naphthalene-2,3-diol Authors: Marsh, M, Hyvonen, M. Deposit date: 2020-01-27 Release date: 2021-03-03 Last modi

Protein Data Bank Japan2024-03-06 更新50

Supporting Information Data for the Publication "Predicting Ligand Binding Modes by Scaffold-Guided Structure Refinement"

配体结合

结构引导药物设计

This dataset is part of the supporting information for the publication "Predicting Ligand Binding Modes by Scaffold-Guided Structure Refinement" by Pletzer-Zelgert et.al. It contains a directory for

DataCite Commons2026-04-21 更新30

Structure-guided design of partial agonists at an opioid receptor

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