Selected relationships between the 47 putative master regulators and the 5 functional categories with published evidence.

The labels “A”, “A”, “I”, and “I”, and “” indicate the number of the five modulator modes of action for the relationship between a regulator and its target included in the functional gene set: “the activation of a regulator on the expressions of its target genes with the functional category was increased by the modulator”, “inhibition increased”, “activation decreased”, “inhibition decreased”, and “the modulator mode of action is not determined”, respectively.