A Prospective Cohort Study to Assess Longitudinal Immune Responses in Hospitalized Patients With COVID-19 (DAIT-COVID-19-002)

This surveillance study will collect detailed clinical, laboratory, and radiographic data in
coordination with biologic sampling of blood and respiratory secretions and viral shedding in
nasal secretions in order to identify immunophenotypic and genomic features of COVID-19
-related susceptibility and/or progression. The aim: for the results obtained from this study
to assist in generating hypotheses for effective host-directed therapeutic interventions, to
help to prioritize proposals for such interventions, and/or optimize timing for
administration of host-response directed therapeutics.