Crystal Structure Analysis of Bovine Carbonic Anhydrase II to 4-2-methyl-1,3-oxazol-5-ylbenzenesulfonamide

Crystal Structure Analysis of Bovine Carbonic Anhydrase II to 4-2-methyl-1,3-oxazol-5-ylbenzenesulfonamide Descriptor: 4-(2-methyl-1,3-oxazol-5-yl)benzenesulfonamide, ACETATE ION, Carbonic anhydrase 2, ... Authors: Stoliarskaia, M.Y, Nikonov, O.S. Deposit date: 2026-02-12 Release date: 2026-02-25 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.5 Å) Cite: X-ray analysis of complexes of carbonic anhydrase II with 1,3-oxazole-containing sulfonamide derivatives elucidates the structural basis for their exceptionally high inhibitory potency. Acta Crystallogr.,Sect.F, 82, 2026牛碳酸酐酶II与4-(2-甲基-1,3-恶唑-5-基)苯磺酰胺的晶体结构分析 描述符：4-(2-甲基-1,3-恶唑-5-基)苯磺酰胺（4-(2-methyl-1,3-oxazol-5-yl)benzenesulfonamide）、乙酸根离子、碳酸酐酶2（Carbonic anhydrase 2）…… 作者：Stoliarskaia, M.Y.、Nikonov, O.S. 提交日期：2026-02-12 发布日期：2026-02-25 最后修改日期：2026-04-15 研究方法：X射线衍射（1.5埃） 引用文献：含1,3-恶唑类磺酰胺衍生物的碳酸酐酶II复合物的X射线分析揭示其极高抑制活性的结构基础. Acta Crystallogr.,Sect.F, 82, 2026