Human thymidylate kinase complexed with the bisubstrate inhibitor AZTP5A
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https://pdbj.org/mine/summary/1e9a
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Human thymidylate kinase complexed with the bisubstrate inhibitor AZTP5A Descriptor: MAGNESIUM ION, P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE, THYMIDYLATE KINASE Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
创建时间:
2000-10-10



