Alterations of gut microbiome, metabolome and lipidome in Takayasu arteritis

Mounting evidences have linked microbiome and metabolome to systemic autoimmunity and cardiovascular diseases. A rare overlapped disease, Takayasu arteritis(TA), has limited information. This study aimed to characterize discriminatory gut dysbiosis, host metabolite and lipid profiles, and their crosstalk with disease phenotypes in TA.