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Enhancer-activated RET confers protection against oxidative stress to the MLL-rearranged acute myeloid leukemia cells

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NIAID Data Ecosystem2026-05-01 收录
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RET expression is upregulated in AML subtypes harboring genetic fusions of MLL-1 genes compared to age-matched healthy donors and other AML subtypes. In addition, we identify a novel epigenetic mechanism of RET overexpression in MLL-rearranged AML. examination of chromatin accessibility in CD34 and MOLM13 cells

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2024-03-04
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