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Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

NIAID Data Ecosystem2026-03-08 收录

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细胞周期G1期研究

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA290188 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-07-17

早衰症

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Progeroid syndromes are rare genetic disorders that phenotypically resemble natural aging. Despite identification of causal mutations, mechanisms that generate their clinical manifestations remain elu

NIAID Data Ecosystem70

Global early replication disrupts gene expression and chromatin conformation in a single cell cycle: MNAse-Seq mapping

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染色质景观调控

The early embryonic divisions of many organisms, including fish, flies and frogs are characterised by a very rapid S-phase caused by high rates of replication initiation. In somatic cells, S-phase is

NIAID Data Ecosystem70

Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes in S. cerevisiae (HTS)

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染色体空间组织

Forkhead Box (Fox) proteins share the Forkhead domain, a winged-helix DNA binding module, which is conserved among eukaryotes from yeast to humans. These sequence-specific DNA binding proteins have be

Alliance of Genome Resources60

Arabidopsis thaliana Chromosome 4 Replicates in Two Phases That Correlate with Chromatin State

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染色质表观遗传调控

DNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conse

NIAID Data Ecosystem70

Functional Centromeres Determine the Activation Time of Pericentric Origins of DNA Replication in Saccharomyces cerevisiae

着丝粒功能

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The centromeric regions of all Saccharomyces cerevisiae chromosomes are found in early replicating domains, a property conserved among centromeres in fungi and some higher eukaryotes. Surprisingly, li

NIAID Data Ecosystem60

Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

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