Cancer is an urgent public health issue with a very huge number of cases all over the world expected to increase by 2040. Despite improved diagnosis and therapeutic protocols, it remains the main lead
The random mutation and natural selection phenomenon act in a mathematically predictable behavior which when understood leads to approaches to reduce and prevent the failure of the use of these select
Our observation suggest that ADAR may play important role to maintain GSC stemness. In order to address this hypothesis, we abrogated the expression of ADAR in GSCs using two distinct short and non-ov
Diverse combination therapies are being investigated to overcome the limitations of immune checkpoint inhibitors. However, determining the optimal combination therapy remains a challenge. Herein, we d
Eighteen independent neurospheres derived from patients affected by primary glioblastoma were grouped into “classical”, “mesenchymal” or “proneural” subtypes according to analysis of genetic lesions a
