SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS

Protein Data Bank Japan2023-10-18 更新2026-03-21 收录

核受体RORγt结构生物学

RORγt激动剂研发

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https://pdbj.org/mine/summary/6w9h 数据链接链接失效反馈

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SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS Descriptor: 4-{(3R)-3-[4-(benzyloxy)phenyl]-3-[(4-fluorophenyl)sulfonyl]pyrrolidine-1-carbonyl}-1lambda~6~-thiane-1,1-dione, Nuclear receptor ROR-gamma, Steroid receptor coactivator 1 fusion Authors: Sack, J.S. Deposit date: 2020-03-23 Release date: 2020-04-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.995 Å) Cite: Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (ROR gamma t) agonists. Bioorg.Med.Chem.Lett., 30, 2020

取代苄氧基三环类化合物作为视黄酸相关孤儿受体γt（retinoic acid-related orphan receptor gamma t, RORγt）激动剂描述符：4-{(3R)-3-[4-(苄氧基)苯基]-3-[(4-氟苯基)磺酰基]吡咯烷-1-羰基}-1λ⁶-噻烷-1,1-二酮、核受体RORγt、类固醇受体共激活因子1融合体作者：Sack, J.S. 存库日期：2020-03-23 发布日期：2020-04-29 最后修改日期：2023-10-18 测试方法：X射线衍射（1.995埃）引用文献：取代苄氧基三环类化合物作为视黄酸相关孤儿受体γt（retinoic acid-related orphan receptor gamma t, RORγt）激动剂. Bioorg.Med.Chem.Lett., 30, 2020

创建时间：

2020-03-23

SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS

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