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Crystal structure of the antagonist form of human glucocorticoid receptor

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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Crystal structure of the antagonist form of human glucocorticoid receptor Descriptor: 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, GLYCEROL, Glucocorticoid receptor, ... Authors: Schoch, G.A, Benz, J, D'Arcy, B, Stihle, M, Burger, D, Thoma, R, Ruf, A. Deposit date: 2009-04-21 Release date: 2009-12-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations J.Mol.Biol., 395, 2010

人糖皮质激素受体(Glucocorticoid receptor)拮抗剂构象的晶体结构 描述项:配体为11-(4-二甲基氨基苯基)-17-羟基-13-甲基-17-丙-1-炔基-1,2,6,7,8,11,12,13,14,15,16,17-十二氢-环戊并[a]菲-3-酮,体系包含甘油(GLYCEROL)与糖皮质激素受体(Glucocorticoid receptor)等组分 作者:Schoch, G.A、Benz, J、D'Arcy, B、Stihle, M、Burger, D、Thoma, R、Ruf, A 提交日期:2009-04-21 发布日期:2009-12-01 最后修改日期:2023-11-01 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.8埃 引用文献:《糖皮质激素受体的分子开关:活性与被动拮抗剂构象》,J.Mol.Biol., 395, 2010

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2009-04-21
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