five

Drug Approvals KG version 0.3.5

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DataCite Commons2024-12-22 更新2025-01-06 收录
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https://figshare.com/articles/dataset/Drug_Approvals_KG_version_0_3_5/28079567
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<b>Description</b>: The Drug Approvals KG, created and maintained by the Multiomics Provider, provides assertions about regulatory approvals of drug interventions for treating diseases, and observations of off-label use of drug interventions. These assertions and observations are derived through integration of content from DailyMed and the FDA's adverse-event reporting system (FAERS).<b>Example</b>: The Drug Approvals KG shows that leuprolide treats prostate cancer. This assertion is supported by 11 approved New Drug Applications, including NDA019732, and 7 product labels, including LEUPROLIDE ACETATE DEPOT- leuprolide acetate kit. The Drug Approvals KG also shows that risperidone is applied to treat ADHD, off-label. This observation is supported by tens of thousands of case reports in FAERS.The graph currently uses biolink:treats and biolink:applied_to_treat as predicates. Node categories include biolink:SmallMolecule, biolink:ChemicalEntity, and biolink:MolecularMixture for the interventions, and biolink:Disease and biolink:PhenotypicFeature for the conditions.
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figshare
创建时间:
2024-12-22
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