Citrate Synthase (CitA) in Mycobacterium tuberculosis modified by Ebselen at C143 residue

Citrate Synthase (CitA) in Mycobacterium tuberculosis modified by Ebselen at C143 residue Descriptor: CITRATE ANION, N-phenyl-2-selanylbenzamide, citrate synthase Authors: Pathirage, R, Ronning, D. Deposit date: 2023-03-25 Release date: 2023-06-07 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023结核分枝杆菌（Mycobacterium tuberculosis）中的柠檬酸合酶（Citrate Synthase, CitA）在第143位半胱氨酸残基（C143）处经依布硒啉（Ebselen）修饰。数据集描述：柠檬酸阴离子、N-苯基-2-硒代苯甲酰胺、柠檬酸合酶。作者：Pathirage, R、Ronning, D。提交日期：2023-03-25；发布日期：2023-06-07；最后修改日期：2024-10-09。实验方法：X射线衍射（2.7 Å）。引用文献：结核分枝杆菌CitA的活性受半胱氨酸氧化与丙酮酸结合调控，《Rsc Med Chem》，2023年，第14卷。