Additivity of DZNep and bortezomib proapoptotic effects on MM cells.
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JJN3 DZNep-sensitive cells and LP1 DZNep-resistant cells were either treated with vehicle or DZNep 1 µM or bortezomib (Bort) 10–25 nM for 48 h or sequentially first with bortezomib for 24 h then DZnep for 24 h. Apoptosis was estimated after anti-APO2.7 staining of cells and cytometry sorting. At least, 2×104 events were gated. Additivity of DZNep and bortezomib proapoptotic effects on MM cells.
创建时间:
2014-09-25



