Skeletal muscle phenotype of the DE50-MD dog: fibre profiles and revertants

This dataset contains all fibre profile and revertant fibre histology data used in the manuscript

The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy

Included are:

1) Images: all raw images used for measurement of fibre profiles (Minimum Feret Diameter, Cross sectional area) in either .zvi (Zeis Vision Image) or .tif format. Images are either staining with picrosirius red, or immunolabelled for the basement menbrane marker perlecan (where indicated, alongside either dMHC or Dys2, for identification of revertant fibres). Also included, where appropriate, are imageJ-compatible masks, ROI manager and results files for each image.

2) Raw data: all per-image MFD/CSA data in excel format.

3) a summary document (excel spreadsheet) collecting all MFD data together, along with median values, coefficients of variation and normalisation to femur length/bodyweight, along with a summary of all revertant counts