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scRNAseq of mouse proliferative vitreoretinopathy

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE274480
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We performed single cell transcriptional profiling of mouse proliferative vitreoretinopathy (PVR), to decipher the molecular mechanisms underlying mouse PVR fibrogenesis. In this study, through combination of the single-cell transcriptional profiling and genetic tracing, we provided comprehensive discrimination for the sources of PVR-associated fibroblasts during ocular wound healing. Single-cell RNA-seq (10X) data from disperesed proliferative vitreoretinopathy of dispase induced mice. Dispase (Sigma) was intravitreal injected in 8-week-old C57BLJ/6 mice and sacrificed in 7 days.
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2025-09-05
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