PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane

Formation of a complex with MTMR9 results in a 4-fold increase of the phosphatidylinositol-3-phosphatase catalytic activity of MTMR8 and a modest increase of the catalytic activity of MTMR6 (Zou et al. 2012).

MTMR9与复合物的形成导致MTMR8的磷脂酰肌醇-3-磷酸酶催化活性增加4倍，同时MTMR6的催化活性略有提升（Zou等，2012年）。