Cryo-EM structure of Gi1-bound mGlu2-mGlu4 heterodimer

Cryo-EM structure of Gi1-bound mGlu2-mGlu4 heterodimer Descriptor: 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine, ... Authors: Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B. Deposit date: 2023-05-12 Release date: 2023-06-21 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers. Cell Res., 33, 2023结合Gi1蛋白的mGlu2-mGlu4异二聚体的冷冻电镜（Cryo-EM）结构 描述符：1-丁基-3-氯-4-(4-苯基哌啶-1-基)吡啶-2-酮、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、5-甲基-N-(4-甲基嘧啶-2-基)-4-(1H-吡唑-4-基)-1,3-噻唑-2-胺…… 作者：Wang X、Wang M、Xu T、Feng Y、Han S、Zhao Q、Wu B 存档日期：2023-05-12 发布日期：2023-06-21 最后修改日期：2024-10-16 实验方法：电子显微术（分辨率3.6 Å） 引用文献：《mGlu2-mGlu3与mGlu2-mGlu4异二聚体的二聚化与激活的结构机制》，《Cell Research》，第33卷，2023年