Comparison of Operator Required to Complete Total Length Analysis.

Time required to complete the analysis by manually tracing or by Pipeline (all times in minutes). In the present study (data displayed in Figure 7) it took each operator approximately 240 minutes to complete the analysis by manually tracing tube-like structures. Completing the same analysis in Pipeline took approximately 7 minutes to set up the analysis and 10 minutes to examine the output images to verify an accurate result. When re-analyzing the data from Chu et al, it took only 1 minute to set up the analysis in Pipeline and 5 minutes to verify an accurate result as opposed to 180 minutes to complete the analysis through manual tracing.