Fat_challenge_tests. Fat_challenge_tests

Exploration of new markers that define impaired metabolic flexibility using an acute postprandial challenge test. Healthy subjects underwent a 4-week high-fat high-calorie diet. High-fat challenges were performed in these subjects before and after the diet and in subjects with the metabolic syndrome. Overall design: Whole blood gene expression was measured from total blood RNA at fasting and at 120 and 360 min after the high-fat challenges.