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Genome-wide analysis of DNA replication stress in the Human Neuroblastoma Cell Line IMR32 by TrAEL-seq

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE186122
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TrAEL-seq was used to assess the impact of Triapine (3AP), a RRM2 inhibitor, on replication fork accumulation and changes to the replication profile of IMR32 cells. TrAEL-seq was performed on IMR32 cells cultured (as described below) in duplicate, in either untreated media or in media containing 0.1% DMSO with or without 3AP treatment (689.5 nM).
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2022-08-02
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