Aspirin-exacerbated respiratory disease (AERD) represents a particularly severe endotype of chronic rhinosinusitis with nasal polyps (CRSwNP), which affects around 10-16% of CRSwNP patients. AERD is c
The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects hav
Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for repr
During oncogenic transformation, cells acquire genetic mutations that override the normal mechanisms regulating cellular proliferation. Excessive expression of activating transcription factor 4 (ATF4)
These data have been processed by Cell Ranger (v8.0, 10X Genomics). Samples: HCT116 WT, HCT116 UHRF1-AID1 cells, HCT116 DNMT1-AID1 cells, HCT116 UHRF1-AID1/DNMT1-AID1 cells. Treatment: All cells wer