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Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKa2 to inhibit AMPK activity and induce mitochondrial dysfunction

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP567595
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To analyze the mRNA profile of DUBs in diabetic heart, we performed a scRNA-seq of heart cells from the wild type (WT) mice and db/db mice, a typical T2DM model mouse. Overall design: wild type (WT) mouse (n=1) and typical T2DM model mouse (n=1)
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2025-08-01
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