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A CpG island-encoded mechanism protects genes from premature transcription termination

NIAID Data Ecosystem2026-03-14 收录

转录终止调控

CpG岛功能机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199805 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-03-02

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非编码RNA转录

RNA Seq and ChIP-exo experiments related to this project Overall design: Four RNA-Seq biological replicates each for deletion mutant (RTR1, RRP6, RTR1 RRP6) and reference cells (WT). Rpb3 and Nrd1 ChI

NIAID Data Ecosystem50

CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation.

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RNA加工

CDK9 is a kinase critical for the productive transcription of protein-coding genes by RNA polymerase II (pol II). As part of P-TEFb, CDK9 phosphorylates the carboxyl-terminal domain (CTD) of pol II an

NIAID Data Ecosystem20

Glc7/PP1 triggers Paf1 complex dissociation from RNA polymerase II to enable transcription termination

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RNA聚合酶复合体

The mechanisms that control the dynamic composition of RNAPII elongation complexes govern major transitions in the transcription cycle yet are poorly understood. Here, we show that the transcription e

NIAID Data Ecosystem10

A first exon termination checkpoint that preferentially suppresses extragenic transcription [RNASEQ_ZC3H4_C]

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外源转录抑制

Wdr82 and Zc3h4 repress transcription at extragenic sites. Transcriptome analysis to measure transcription in cells depleted of Wdr82, Zc3h4or other known termination factors.

NIAID Data Ecosystem30

Characterization of extended transcripts by RNA-Seq suggests that Rrp6 influences Nrd1-dependent termination

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RNA测序数据分析

Characterization of extended transcripts by RNA-Seq suggests that Rrp6 influences Nrd1-dependent termination

ChEBI2015-04-14 更新10