Crystal structure of CYP142A3 from Mycobacterium ulcerans bound to Cholest-4-en-3-one

Crystal structure of CYP142A3 from Mycobacterium ulcerans bound to Cholest-4-en-3-one Descriptor: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ACETATE ION, Cytochrome P450 142A3, ... Authors: Doherty, D.Z, Bell, S.G, Bruning, J. Deposit date: 2021-10-08 Release date: 2022-10-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.83 Å) Cite: The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum. Acs Infect Dis., 8, 2022

溃疡分枝杆菌（Mycobacterium ulcerans）来源的、与胆甾-4-烯-3-酮结合的CYP142A3晶体结构。结构描述符：(8α,9β)-胆甾-4-烯-3-酮、醋酸根离子（ACETATE ION）、细胞色素P450 142A3（Cytochrome P450 142A3）等。作者：Doherty D.Z.、Bell S.G.、Bruning J. 提交日期：2021-10-08 发布日期：2022-10-05 最后修改日期：2023-10-18 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.83埃（Å）。引用文献：《溃疡分枝杆菌与海分枝杆菌类固醇结合CYP142家族细胞色素P450酶的结构》，刊载于《ACS Infectious Diseases》，2022年第8卷。